Description
Promethazine and codeine
Promethazine and codeine is a prescription oral solution combining an antihistamine (promethazine) and an opioid cough suppressant (codeine) to treat coughs and cold symptoms in adults. It works by calming the nervous system to suppress coughs and reducing allergy symptoms. Due to the potential for abuse, addiction, and serious side effects like slowed breathing, it is for short-term use only.Â
Key Considerations and Warnings:
- Uses:Â Temporarily relieves cough, runny nose, sneezing, and watery eyes associated with colds or allergies.
- Side Effects:Â Common side effects include extreme drowsiness, dizziness, constipation, dry mouth, and blurry vision.
- Serious Risks:Â This combination can cause severe respiratory depression (slowed breathing), particularly in children or those with breathing issues. It is habit-forming and can lead to fatal overdose.
- Interactions:Â Avoid alcohol, as it intensifies sedation and breathing issues.
- Misuse:Â Known as “purple drank” or “lean,” this combination is sometimes misused for its sedative effects.Â

