Description
O-DSMT powder is the raw form of O-desmethyltramadol, a potent opioid analgesic and the primary active metabolite of tramadol
. It acts as a μmu 𝜇 -opioid receptor agonist, featuring roughly 200 times the affinity of tramadol itself, and acts as a norepinephrine reuptake inhibitor. It is often sold as a research chemical, posing high addiction risk.
Key details regarding O-DSMT include:
- Pharmacology: O-DSMT functions as a μmu 𝜇
-opioid receptor agonist, which contributes to its analgesic effects, and it also inhibits the reuptake of norepinephrine. - Potency: It is significantly more potent than its parent compound, tramadol.
- Metabolism: While it is the main metabolite of tramadol produced in the liver via CYP2D6, O-DSMT powder is consumed directly.
- Risks: As an opioid, O-DSMT carries risks of addiction, dependence, and respiratory depression.
- Legal Status: It is often sold online as a “research chemical” or “designer drug,” and its legal status varies significantly by jurisdiction, often existing in a legal gray area or being explicitly banned.
Important Safety Note: O-DSMT is a potent opioid substance with a high potential for abuse and physical dependence. It is not approved for human consumption in many regions and can cause serious adverse effects, including respiratory depression, overdose, and death.
